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The “honest” placebo: When drugs still work even though patients know they’re fake

A major review of the placebo effect across a number of clinical conditions in 2010 did conclude that, in general, placebos produced no important beneficial effects. However, homing in on more specific outcomes, the reasonably critical review did admit to finding evidence of beneficial effects in some situations that relied on patient-reported outcomes, such as pain and nausea.

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