11
Oct
2018

Mice eat too much food if their great grandmother did the same

mouse and butter

Long-term effects

Michael Blann/Getty

By Yvaine Ye

When a female mouse is fed a high-fat diet her children, grandchildren and great grandchildren have a greater risk of obesity and addiction — because of changes to the brain reward system.

Diet can mess with the brain. Animal studies have shown that the offspring of mothers consuming a high-fat diet have a less sensitive reward system: they need to consume more food or pleasure-enhancing drugs to feel full or satisfied. Therefore, these individuals are more likely to become obese and addicted to drugs.

Daria Peleg-Raibstein at the Swiss Federal Institute of Technology and …

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