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Cancer drug that inhibits porcupine enzyme could help hearts

“We saw many predictable adverse effects – in bone and hair, for example – but one surprise was that the number of dividing cardiomyocytes (heart muscle cells) was slightly increased,” said Dr. Lum, senior author of the paper, and a member of UTSW’s Hamon Center for Regenerative Science and Medicine. “In addition to the intense interest in porcupine inhibitors as anticancer agents, this research shows that such agents could be useful in regenerative medicine.”

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