Anti-aging senolytics drugs found to improve mice health and lifespan

In the new study, researchers found more evidence that senescent cells are responsible for age-related ailments, and then treated them with senolytic compounds. First, the team injected young four-month-old mice with senescent cells, and found that just two weeks later they showed clear physical signs of aging. Compared to a control group that received injections of non-senescent cells, the walking speed, muscle strength, physical endurance, daily activity levels, food intake and body weight of the test mice were all reduced. At the same time, the numbers of senescent cells in their bodies increased, indicating the effect was spreading to healthy cells.

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